Progress in medicinal chemistry: volume 46
Éditeur :
Elsevier Science & Technology
ISBN :
9780444530189
Date de publication :
8 avr. 2008
Dimensions :
21,0 x 14,0 cm
Poids :
670 g
Langue :
Anglais
Pays d'origine :
Grande Bretagne
Appropriate selection of biochemical targets is one of the most important drivers of cost effectiveness in the discovery of new medicines. This title covers HIV integrase (discovery of the first-in-class inhibitor drug raltegravir), and 11-beta-Hydroxysteroid dehydrogenase (fresh approach to glucocorticoid regulation).