Therapeutic targeting of ras mutant cancers
Auteur :
Stites, Edward C. / Paskvan, Kendra / Kato, Shumei
Éditeur :
Cambridge University Press
ISBN :
9781009073646
Date de publication :
15 sept. 2022
Dimensions :
22,8 x 15,2 x 0,3 cm
Poids :
80 g
Format :
Trade paperback (US)
Langue :
Anglais
Pays d'origine :
Grande Bretagne
The KRAS oncogene is believed to be the most common single nucleotide variant oncogene in human cancer. Historically, efforts to target KRAS and the other RAS GTPases have struggled. More recently, efforts have focused on identifying and exploiting features unique to specific oncogenic mutations.