Phytochemicals targeting tumor microenvironment in gastrointestinal cancers
Éditeur :
Springer Nature Switzerland AG
ISBN :
9783030484040
Date de publication :
23 oct. 2020
Dimensions :
23,5 x 15,5 cm
Langue :
Anglais
Pays d'origine :
Suisse
The tumor’s increased cell signalling due to excessive transcription factor activation and increased stellate cell activity leads to collagen deposition formation of a dense stroma around the tumor, which prevents drugs from reaching the malignant cells.