Phase 1 cancer clinical trials: a practical guide
Auteur :
Eisenhauer, Elizabeth A / Twelves, Christopher / Buyse, Marc
Éditeur :
Oxford University Press
ISBN :
9780198567196
Date de publication :
20 juil. 2006
Dimensions :
23,2 x 15,1 x 2,0 cm
Poids :
563 g
Langue :
Anglais
Pays d'origine :
Grande Bretagne
Phase I trials are the first step in the study of novel therapeutic approaches. They aim to identify the recommended dose, schedule and pharamcologic behaviour of new drugs, and to describe the adverse effects of treatment. This practical guide discusses the design, conduct, analysis and ethical aspects of Phase I cancer trials.