Crispr guide rna design: methods and protocols
Éditeur :
Springer-Verlag New York Inc.
ISBN :
9781071606896
Date de publication :
16 sept. 2021
Dimensions :
25,4 x 17,8 cm
Langue :
Anglais
Pays d'origine :
USA
Beginning with a section on computational design of target-specific guide RNAs, the book continues by covering chemical modifications to alter guide RNA stability, specificity, and efficiency, as well as to create inducible guide RNAs, append additional functional domains, and express guide RNAs in a conditional manner.