Polyploidization and cancer
Éditeur :
Springer-Verlag New York Inc.
ISBN :
9781493951437
Date de publication :
23 août 2016
Dimensions :
25,4 x 17,8 cm
Langue :
Anglais
Pays d'origine :
USA
Limiting genome replication to once per cell cycle is vital for maintaining genome stability. Although polyploidization is of physiologically importance for several specialized cell types, inappropriate polyploidization is believed to promote aneuploidy and transformation.