Methods and applications of sample size calculation and recalculation in clinical trials
Auteur :
Kieser, Meinhard
Éditeur :
Springer Nature Switzerland AG
ISBN :
9783030495305
Date de publication :
20 nov. 2021
Dimensions :
23,5 x 15,5 cm
Langue :
Anglais
Pays d'origine :
Suisse
This book provides an extensive overview of the principles and methods of sample size calculation and recalculation in clinical trials. Blinded sample size recalculation procedures for internal pilot study designs are considered, as well as methods for sample size reassessment in adaptive designs that use unblinded data from interim analyses.