Progress in the chemistry of organic natural products 115
Éditeur :
Springer Nature Switzerland AG
ISBN :
9783030648558
Date de publication :
3 avr. 2022
Dimensions :
23,5 x 15,5 cm
Langue :
Anglais
Pays d'origine :
Suisse
The following chapter presents the development of the intriguing plant-derived sesquiterpene lactone, thapsigargin, a potent inhibitor of the enzyme, SERCA (sarco-endoplasmic Ca2+ ATPase), which has potential as a lead compound to treat cancer.