Computing characterizations of drugs for ion channels and receptors using markov models
Auteur :
Tveito, Aslak / Lines, Glenn T.
Éditeur :
Springer International Publishing AG
ISBN :
9783319807089
Date de publication :
22 avr. 2018
Dimensions :
23,5 x 15,5 cm
Langue :
Anglais
Pays d'origine :
Suisse
Flow of ions through voltage gatedchannels can be represented theoretically using stochastic differentialequations where the gating mechanism is represented by a Markov model. The flow through achannel can be manipulated using various drugs, and the effect of a given drugcan be reflected bychanging the Markov model.